MULTI COLUMN
DISTILLATION PLANT
(WFI PLANT)
The Multi Column Distillation plant produces low conductivity pyrogen / endotoxin free Water For Injection (WFI) by stage distillation process. As the name suggests the unit consists of a series of pressure vessels in the form of columns / stills which are inter connected. Boiler steam is utilised only in the first column to produce pure steam and remaining columns utilize this pure steam to produce furthermore pure steam. During this heat exchange process, pure steam condenses. Additional condensers are provided on top to condense the pure steam completely to produce WFI. The plant is designed for maximum heat recovery and hence very economical in operating cost.
APPLICATIONS
Multi Column Distillation Plant produces WFI (Water For Injection) WFI is required for
• LVP / SVP Manufacturing
• Ophthalmic Products
• Insulin Manufacturing
• Vaccines Manufacturing
• Nasal Products
• Any Kind of Liquid or Dry Sterile Products
Features
• Capacity varies from 5 to 6,000 litres per hour
• Designed and manufactured as per ASME BPE and cGMP guidelines
• The WFI generated meets USP, EP, BP and IP standards
• Phase separation is based on falling film evaporator technology
• Specially designed and constructed to remove pyrogen / endotoxin
• Designed and constructed to achieve 100 % drainability
• All wetted parts are made from AISI 316L stainless steel and rest are made of AISI 304 stainless steel
• All water contact surfaces are finished to electro polished to Ra < 0.4 and are crevice free
• IPC & PLC based 21 CFR part 11 complied fully automatic control panel with online printing facility
• Double tube sheet construction for the first column, where boiler steam is present
• Our compact and optimised design required minimum human interference. This means low maintenance and low operational cost
• Complete set of documentation and certificates to ensure compliance with regulatory authority. We provide DQ, OQ, IQ, FAT & SAT. Also assist client to develop PQ